Estrogen and Cognitive Functioning in Women

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Estrogen and cognitive functioning in women.

Research in basic neuroscience has provided biological plausibility for the hypothesis that estrogen replacement therapy (ERT) would protect against cognitive aging in healthy women. The weight of the evidence from randomized controlled trials of estrogen and cognition in women shows that this hormone preferentially protects verbal memory in postmenopausal women, whereas findings from observati...

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Estrogen and cognitive functioning in women: lessons we have learned.

Extant research findings allow several conclusions regarding the relationship between estrogen and cognitive functioning across the female life span. First, performance on tests of verbal memory fluctuates in concert with physiological changes in ovarian hormone production during the menstrual cycle and during pregnancy and the postpartum period. Estrogen therapy (ET) prevents the decrease in v...

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Life-time estrogen exposure and cognitive functioning in later life.

CONTEXT While recent studies suggest that exogenous estrogen treatment could help reduce age-related cognitive decline and delay the onset of dementia, this has not been found consistently. Few studies have considered the influence of life-time estrogen exposure which may have an independent effect on cognition and/or modulate treatment response. OBJECTIVE The aim of this study was to examine...

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Iron treatment normalizes cognitive functioning in young women.

BACKGROUND Evidence suggests that brain iron deficiency at any time in life may disrupt metabolic processes and subsequently change cognitive and behavioral functioning. Women of reproductive age are among those most vulnerable to iron deficiency and may be at high risk for cognitive alterations due to iron deficiency. OBJECTIVE We aimed to examine the relation between iron status and cogniti...

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Estrogen replacement therapy and cognitive functioning in the Atherosclerosis Risk in Communities (ARIC) Study.

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ژورنال

عنوان ژورنال: Endocrine Reviews

سال: 2003

ISSN: 0163-769X,1945-7189

DOI: 10.1210/er.2001-0016